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Introduction: Pancreaticoduodenectomy, often referred as Whipple procedure, is the most common surgery performed to treat pancreatic cancers. Periampullary carcinomas are described as tumors arising within 2 cm of the major papilla in the duodenum. These tumors are of four different types: ampullary carcinoma, biliary carcinomas (intrapancreatic distal bile duct), pancreatic (head–uncinate process), and duodenal (mainly from the second part).
Objective: The aim of this study was to analyze the histopathological features of Whipple-resected specimen received at Gajra Raja Medical College, Gwalior during the period of 2 years.
Method: A retrospective study was done of 22 cases of Whipple resections received during 2020-22. All relevant histopathological details pertaining to gross, microscopic diagnosis, grading, staging were comprehensively studied. Reporting was done in accordance to CAP protocol.
Result: Out of 22 patients 12 (54.54%) were males and 10(45.45%) females. Ratio was 1.2:1. Mean age was 58.4 years. Most common site of tumour was periampullary, 14 [63.6%] followed by pancreatic head, 4[18.18%]; distal common bile duct, 3[13.6%]; duodenum 1[4.5%]. Most common histological type was adenocarcinoma, 21[95.45%]. Lymph node was positive in 5 cases [22.72%]. Lymphovascular invasion was seen in 5 cases (22.72%) & Perineural invasion was seen in 6 [27.27%]cases.
Conclusion: The current analysis shows that periampullary adenocarcinoma is the most common subtype.
Keywords:
Pancreaticoduodenectomy, Whipples’s procedure, CAP protocol, Periampullary Adenocarcinoma
Cite Article:
"Analysis of Whipple`s Resection Specimens For Two Year Period In Tertiary Care Centre In Cenral India: A Histopathological Study", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 4, page no.90 - 98, April-2023, Available :http://www.ijrti.org/papers/IJRTI2304016.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator