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The aim and objective of this study to formulate and evaluate the herbal based microneedle patch for an acne infection here, totally two herbal extracts were used (ie) hydroalcoholic extracts of Curcuma longa and Azadirachta indica, both the extracts can potentially inhibits the activity of many bacterial pathogens, these extracts already used in many cosmetic formulations for to control the acne infection. PVP and PVA were used as polymer for dissolving microneedle patch because of its better compatibility studies and physical nature. There are three different microneedle patches were formulated (F1, F2 and F3) and standardization procedure were done with this patches. By the results of standardization F2 formulation is better one, it was selected for further evaluation studies of SEM analysis and antimicrobial studies. Till now there are 11 types of bacterial stains prominently affects the human population, among these two stains (ie) Staphylococcus aureus, Micrococcus luteus were collected Antimicrobial study was performed using F2 microneedle patch, it’s potentially inhibits the growth of microorganism. In future in-vitro drug releasing study and in-vivo animal studies can be continued for F2 formulation.
Keywords:
Microneedle patch, Novel dosage forms, TDDS, Acne infection, SEM analysis.
Cite Article:
"FORMULATION AND EVALUATION OF HERBAL BASED MICRONEEDLE PATCH FOR AN ACNE INFECTION", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 4, page no.375 - 384, April-2023, Available :http://www.ijrti.org/papers/IJRTI2304064.pdf
Downloads:
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator