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Systemic lupus erythematosus (SLE) is an autoimmune disease. It is distinguished by the presence of autoantibodies that are directed against nuclear antigens. Because it affects multiple systems, patients might appear in a wide variety of ways. The complicated aetiopathogenesis of this illness is reflected in the clinical variability of the condition, which emphasises the significance of genetic determinants and individual vulnerability to environmental influences. Every organ in the body is susceptible to SLE. Rash, arthritis, and exhaustion are the most typical symptoms. SLE can induce nephritis, neurological issues, anaemia, and thrombocytopenia at the more severe end of the spectrum. Substantial titres are acknowledged to be of 1:80 or greater. Relapsing and remitting SLE has three therapeutic goals: managing acute episodes of potentially fatal illness, reducing the likelihood of flares during times of relative stability, and managing the less serious but frequently incapacitating day-to-day symptoms. Corticosteroids and immunosuppressive therapies are typically reserved for major organ involvement; anti-CD20 monoclonal antibody is now used in patients with severe disease who have not responded to conventional treatments. Despite major advancements in prognosis brought about by the use of corticosteroids and immunosuppressive medications, SLE still has a sizable effect on the mortality and morbidity of people affected.
Keywords:
Systemic lupus erythematosus, lupus.
Cite Article:
"Systemic Lupus Erythematosus - A Review ", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 5, page no.144 - 146, May-2023, Available :http://www.ijrti.org/papers/IJRTI2305020.pdf
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000205185
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator