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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 115
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Published Paper Details
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| Paper Title: | Development and Evaluation of Topical Nanosponges Based Gel Containing Caffeine |
| Authors Name: | Divyesh Bora , Kalpesh Kedare , Tushar Patil , Kalyani Ahire |
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| Author Reg. ID: |
IJRTI_188137
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| Published Paper Id: | IJRTI2310009 |
| Published In: | Volume 8 Issue 10, October-2023 |
| DOI: | |
| Abstract: | A Topical drug conveyance framework is a method for conveying a prescription that is applied on to a specific part of the body, ordinarily the skin, to treat different diseases. Nanosponges act for the purpose of demonstrative devices or to convey restorative specialists to explicitly designated destinations in a controlled way, particularly for ineffectively water-dissolvable medications like caffeine. Nanosponges are little circular particles containing depressions where drug atoms can be put away. The caffeine nanosponges were ready by emulsion dissolvable dispersion technique, utilizing different extents of caffeine(drug): ethylcellulose(polymer) disintegrated in 20ml of dichloromethane and gradually added to the distinct measure of polyvinyl liquor in 100ml of the fluid nonstop stage. The response blend is saved for mixing at 1000 rpm for 2 hrs. Nanosponges were ready for the drug: polymer proportion of 1:1, 1:0.25, 1:0.50, 1:0.75, 1:1.25, 1:1.50. Arranged nanosponges were assessed for weight consistency, molecule size examination, disintegration testing, and microscopy. The nanosponges were additionally figured out into an effective gel by utilizing carbopol 940 polymer. The gel was assessed based on spreadability, consistency, scent, variety, in vitro discharge, and steadiness. From the review, it was presumed that the gel displayed palatable dependability and promising medication discharge. The definition was viewed as a reasonable possibility for the improvement of nanosponges stacked skin gel for helpful use in the treatment of cellulite. |
| Keywords: | Cellulite, Nanosponges, Particle size analysis |
| Cite Article: | "Development and Evaluation of Topical Nanosponges Based Gel Containing Caffeine", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 10, page no.44 - 55, October-2023, Available :http://www.ijrti.org/papers/IJRTI2310009.pdf |
| Downloads: | 000205198 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2310009
Registration ID:188137
Published In: Volume 8 Issue 10, October-2023
DOI (Digital Object Identifier):
Page No: 44 - 55 Country: Dhule, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2310009 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2310009 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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