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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 115
Article Submitted : 19439
Article Published : 8041
Total Authors : 21252
Total Reviewer : 769
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| Paper Title: | Formulation and Evaluation of Gelatin Microsphere of Diclofenac Sodium |
| Authors Name: | Amol Gajanan Jadhao , Mr. Amol Gajanan Jadhao , Prathmesh Rajesh Dungu , Miss. Jayshri Bhimrao Sanap |
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IJRTI_188488
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| Published Paper Id: | IJRTI2311053 |
| Published In: | Volume 8 Issue 11, November-2023 |
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| Abstract: | This research investigates the utilization of microspheres as an innovative approach in designing drug delivery systems that offer controlled and sustained drug release. The study concentrates on optimizing drug release profiles and enhancing the efficiency of drug entrapment through the precise application of the phase separation coacervation technique for microsphere fabrication. In contrast to traditional methods targeting inflammatory mediators, this study pioneers a unique strategy by integrating Diclofenac sodium into microspheres. These precisely engineered particles exhibit exceptional morphology and significantly improved drug entrapment efficiency. A comprehensive analysis of the entrapment efficiency and in-vitro drug release patterns confirms that Diclofenac Gelatin microspheres demonstrate outstanding stability and structural integrity. The findings underscore the substantial benefits of Diclofenac Gelatin microspheres, emphasizing how the gelatin component enhances drug stability and precise dosage encapsulation. Furthermore, these microspheres facilitate targeted delivery tailored to specific tissue types, promising enhanced therapeutic outcomes and reduced side effects in drug administration. The distinct characteristics of gelatin microspheres present a promising avenue for advancing drug delivery systems, holding potential for improved patient compliance and efficacy in clinical applications. |
| Keywords: | Gelatin Microsphere, Diclofenac Sodium, Diclofenac Gelatin Microsphere, In-vitro Drug Studies and Microcarrier. |
| Cite Article: | "Formulation and Evaluation of Gelatin Microsphere of Diclofenac Sodium", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.8, Issue 11, page no.371 - 384, November-2023, Available :http://www.ijrti.org/papers/IJRTI2311053.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2311053
Registration ID:188488
Published In: Volume 8 Issue 11, November-2023
DOI (Digital Object Identifier):
Page No: 371 - 384 Country: Buidana, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2311053 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2311053 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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