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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 114
Article Submitted : 18913
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Total Authors : 20931
Total Reviewer : 760
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| Paper Title: | Immune Thrombocytopenia Purpura |
| Authors Name: | Shreya Shastri , Dr. Blessy K George , Dr. Shibi Mary Thomas |
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| Author Reg. ID: |
IJRTI_188915
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| Published Paper Id: | IJRTI2401053 |
| Published In: | Volume 9 Issue 1, January-2024 |
| DOI: | |
| Abstract: | Idiopathic thrombocytopenia purpura is an autoimmune condition marked by isolated thrombocytopenia brought on by sped-up platelet eradication and reduced platelet synthesis. Although both antibody-mediated and/or T cell-mediated platelet destruction are important mechanisms, the etiology of ITP is yet unknown. Additionally, it is now understood that the role of the bone marrow niche as well as T cell dysfunction and cytokine imbalances are crucial. ITP is linked to a lot of bleeding and frequent bruising because of low platelet counts. According to recent research, several variables, including defective thrombopoiesis and alterations in the immune response that cause platelet destruction under pathological circumstances, contribute to reduced platelet numbers in ITP. The only time a clinical diagnosis may be made is after all other potential causes of thrombocytopenia have been ruled out by laboratory and historical analysis. The first-line therapy for adult ITP includes corticosteroids, intravenous immunoglobulin, or intravenous anti-Rh D immune globulin. Adult ITP is commonly treated with rituximab, splenectomy, or thrombopoietin receptor agonists (TPO-RAs; romiplostim or eltrombopag). |
| Keywords: | immune thrombocytopenia, autoimmune, platelets destruction, B cells, T cells, bleeding, ITP treatment. |
| Cite Article: | "Immune Thrombocytopenia Purpura", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 1, page no.303 - 309, January-2024, Available :http://www.ijrti.org/papers/IJRTI2401053.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2401053
Registration ID:188915
Published In: Volume 9 Issue 1, January-2024
DOI (Digital Object Identifier):
Page No: 303 - 309 Country: Bangalore, Karnataka, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2401053 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2401053 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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