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Here we describe an ultra-low-cost origami-based approach for large-scale manufacturing of microscopes,
specifically demonstrating bright field, dark field, and fluorescence microscopes. Merging principles of optical
design with origami enables high-volume fabrication of microscopes from 2D media. Flexure mechanisms created
via folding enable a flat compact design. Structural loops in folded paper provide kinematic constraints as a
means for passive self-alignment. This light, rugged instrument can survive harsh field conditions while providing
a diversity of imaging capabilities, thus serving wide-ranging applications for cost-effective, portable microscopes
in science and education.
Microscope is a device used for the visualization of tiny objects which are not visible to the naked eye. Traditional
microscopes have been crucial for the advancement of contemporary science and medicine. Recent advancements
in the field of microscopy have fueled its exponential growth rate. However, due to their expensive cost and
complicated structure, modern microscopes remain in accessible to the majority of the public. Nonetheless, the
fold scope paper microscope has made it possible for anyone to explore and understand the world of microbes and
organisms. In this review, we have listed fold scope-based research projects in various domains, as well as their
key properties when compared to traditional research microscopes. In addition, we have briefly explored the
impact of a fold scope microscope on public health, clinical diagnostics forensic science, agriculture, basic science,
developmental biology, and education. Moreover, the major drawbacks of paper microscopes and the current
steps being taken to upgrade fold scope and its features are discussed in this review. Finally, we have concluded
with our perspective that the microscope maybe updated to imitate the advancement of a conventional
microscope.
Keywords:
Foldscope, paper microscope, laboratory characteristics
Cite Article:
"Foldscope: Paper microscope for lab characterization ", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 2, page no.140 - 148, February-2024, Available :http://www.ijrti.org/papers/IJRTI2402025.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator