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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: March 2026
Volume 11 | Issue 3
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 22135
Article Published : 8686
Total Authors : 22851
Total Reviewer : 819
Total Countries : 160
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| Paper Title: | Formulation and Evaluation of Prefilled syringes containing low molecular weight heparin in various packaging materials. |
| Authors Name: | Abinaya N , Padmapriya S , Rajalakshmi A N |
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IJRTI_189401
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| Published Paper Id: | IJRTI2403064 |
| Published In: | Volume 9 Issue 3, March-2024 |
| DOI: | |
| Abstract: | Heparin is a glycosaminoglycan family sulfated polysaccharide that is used to treat thrombocytopenia and hemorrhage. For the prevention of venous thromboembolism, low molecular weight heparins (LMWH) are typically recommended over unfractionated heparin due to their similar effectiveness and decreased risk of heparin-induced thrombocytopenia. This work produced low molecular weight heparin injection, packed it in new packaging (prefilled syringes made of polypropylene and cyclo-olefin polymer), and assessed its durability and compatibility against glass, a reference standard material. The study's goal is to construct and assess low molecular weight heparin in prefilled syringes as a unit dosage medication delivery method, with the ultimate goal being the safe and efficient selection of appropriate, compatible packing material. Cyclo-olefin polymer was found to have evaluated values that were comparatively closer to the reference standard (glass) than Polypropylene. As a result, Cyclo-olefin polymer may be a good choice for packaging prefilled heparin syringes. Therefore, cyclo-olefin polymer could be regarded as a new and affordable packaging material for heparin prefilled syringes |
| Keywords: | Xa & IIa activity, Prefilled syringes, Cyclo-olefin polymer, Polypropylene, Glass |
| Cite Article: | "Formulation and Evaluation of Prefilled syringes containing low molecular weight heparin in various packaging materials.", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.9, Issue 3, page no.437 - 445, March-2024, Available :http://www.ijrti.org/papers/IJRTI2403064.pdf |
| Downloads: | 000205283 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2403064
Registration ID:189401
Published In: Volume 9 Issue 3, March-2024
DOI (Digital Object Identifier):
Page No: 437 - 445 Country: karaikal, Puducherry, India Research Area: Health Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2403064 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2403064 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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