 |
International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
|
Issue: March 2026
Volume 11 | Issue 3
Review Result and Publication of Paper within : 2-3 days
Click Here For more DetailsFor Authors
Forms / Download
Published Issue Details
Editorial Board
Other IMP Links
Facts & Figure
Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 22135
Article Published : 8686
Total Authors : 22851
Total Reviewer : 819
Total Countries : 160
Indexing Partner
Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
Published Paper Details
|
|
| Paper Title: | RECENT TECHNIQUES IN THE FORMULATION DEVELOPMENT OF LOW DOSE AND POTENT DRUG MOLECULE |
| Authors Name: | Kumudhavalli D , Rajalakshmi A N , Padmapriya S |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_189353
|
| Published Paper Id: | IJRTI2403072 |
| Published In: | Volume 9 Issue 3, March-2024 |
| DOI: | |
| Abstract: | The sole goal of this current research is to develop an immediate release tablet of thyroid hormone (T4), a low dose and potent drug molecule by adopting recent techniques in the formulation development and to improve and ensure content uniformity in the proposed formulation. Blend uniformity was optimized and compared based on blending time (10,20 and 30 mins) as Process variable using Octagonal blender and Rapid Mixing Granulator. 30th min blend of Rapid Mixing Granulator was taken for formulation of immediate release tablet by Direct compression. FR3 formulation were evaluated for different pre and post compression parameter studies. The results of precompression parameters of FR3 formulation were compared with prescribed limits. It showed that FR3 formulation powder blend exhibit good flow property. The disintegration time of all formulation was found to be 5 mins 30 secs. It is concluded that formulated immediate release tablet of Thyroid hormone (T4) was found to improve and ensure the content uniformity. |
| Keywords: | Thyroid hormone(T4), Blend uniformity, Octagonal blender, Rapid Mixing Granulator, Process optimization. |
| Cite Article: | "RECENT TECHNIQUES IN THE FORMULATION DEVELOPMENT OF LOW DOSE AND POTENT DRUG MOLECULE", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.9, Issue 3, page no.504 - 513, March-2024, Available :http://www.ijrti.org/papers/IJRTI2403072.pdf |
| Downloads: | 000205358 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
| Publication Details: |
Published Paper ID: IJRTI2403072
Registration ID:189353
Published In: Volume 9 Issue 3, March-2024
DOI (Digital Object Identifier):
Page No: 504 - 513 Country: Puducherry, Puducherry, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2403072 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2403072 |
| Share Article: | |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijrti.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
ISSN Details
 |
 |
|
ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
DOI (A digital object identifier)
| Providing A digital object identifier by DOI.ONE How to Get DOI? |
Conference
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Important Details
Join RMS/Earn 300
WhatsApp
Click Here
Click Here
Indexing Partner |
|||
| Copyright © 2026 - All Rights Reserved - IJRTI | |||