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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

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Paper Title: Nutritional Management of Autism Spectrum Disorder
Authors Name: Shubham Kamdi , Sneha Gaurkar , Anup Patekar , Ishwar Kale , Prathmesh Hagawane
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IJRTI_189627
Published Paper Id: IJRTI2404076
Published In: Volume 9 Issue 4, April-2024
DOI:
Abstract: Abstract- Autism Spectrum Disorder (ASD) presents a complex clinical picture characterized by a spectrum of symptoms affecting social communication, behaviour, and cognition. This paper provides an integrated exploration of ASD, focusing on its multifactorial etiology and diverse manifestations. Genetic predisposition, environmental factors, and neurological dysregulation contribute to the pathophysiology of ASD, manifesting in alterations in the gut microbiome, immune dysregulation, and mitochondrial dysfunction. Alongside the core symptoms, individuals with ASD often contend with conditions that are simultaneous, such as depression, anxiety, anxiety disorders, and sensory sensitivities, further complicating diagnosis and management. Nutritional management emerges as a crucial aspect of ASD care, with various dietary approaches and supplementation strategies being explored. The Ketogenic Diet, Gluten-Free Casein-Free Diet, and supplementation with Curcumin and Probiotics are among the interventions scrutinized for their potential efficacy in ameliorating ASD symptoms. Additionally, the impact of food additives on ASD symptomatology underscores the importance of dietary considerations in ASD management. Pharmacotherapy, although not targeted specifically for ASD, plays a role in managing associated symptoms and co-occurring conditions. Antipsychotic medications, SSRIs, and stimulants are among the options utilized to address behavioural and mood disturbances in individuals with ASD. However, medication should be integrated into a comprehensive treatment plan that incorporates behavioural therapies and educational interventions tailored to the individual's needs. Looking forward, ongoing research efforts aim to identify biomarkers for ASD, elucidate genetic and neurobiological mechanisms, and develop targeted treatment strategies. Collaboration between researchers, clinicians, and the autism community is paramount in advancing knowledge and improving outcomes for individuals with ASD. In summary, this comprehensive review provides valuable insights into the multifaceted nature of ASD and underscores the importance of a multidimensional approach encompassing genetics, environment, behaviour, and nutrition in its management.
Keywords: Autism Spectrum Disorder (ASD), Neurodevelopmental disorder, Nutraceuticals, Dietary approaches.
Cite Article: "Nutritional Management of Autism Spectrum Disorder ", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 4, page no.529 - 542, April-2024, Available :http://www.ijrti.org/papers/IJRTI2404076.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2404076
Registration ID:189627
Published In: Volume 9 Issue 4, April-2024
DOI (Digital Object Identifier):
Page No: 529 - 542
Country: Amravati, Maharashtra, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2404076
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2404076
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED, Journal Starting Year (ESTD) : 2016

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