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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
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Issue Published : 112
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| Paper Title: | CYTOMORPHOLOGY OF METASTATIC SQUAMOUS CELL CARCINOMA IN EFFUSIONS; A RETROSPECTIVE STUDY |
| Authors Name: | Sivaranjani Selvaraj , Neeliah Siddaraju , Debasis Gochhait |
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IJRTI_189937
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| Published Paper Id: | IJRTI2405083 |
| Published In: | Volume 9 Issue 5, May-2024 |
| DOI: | |
| Abstract: | Introduction: Metastatic squamous cell carcinomas (SCC), though common, are rarely seen in effusions. According to recent literature, the incidence of metastatic squamous cell carcinoma in body cavity fluids is 0.5 – 2.7%. Hence a misdiagnosis of metastatic SCC is very common. But there are some cytomorphological features which can aid us in the accurate diagnosis. A study of the morphological features was done and the morphological features are described in detail for the diagnosis of metastatic SCC. We aim to study the cytomorphological features of metastatic squamous cell carcinoma in effusion fluids. Material and methods: All effusion fluid specimens reported as positive for malignancy with squamous component from January 2014 to January 2019 were included in the study. Adequate clinical details were collected from the database. Results: In the study period, 21 effusion fluid specimens, which included 10 peritoneal and 11 pleural fluids from 16 patients, were reported as squamous cell carcinoma (SCC). 14 of these cases had histopathological correlation and diagnosis. Diagnosis of metastasis was made either based on established morphological features or when a discrepancy was encountered, aid of immunocytochemistry or immunohistochemistry with p63 facilitated in arriving at the diagnosis. Conclusion: Although rare, SCC can be identified in serous effusions. To prevent misdiagnosis, correlation with clinical history and type of original tumor is necessary, along with increased awareness of the cytomorphological types and IHC overlap between carcinomas. Furthermore, the cytological diagnosis of metastatic SCC will give the patient a dismal prognosis |
| Keywords: | cytology, squamous cell carcinoma, peritoneal fluid, pleural fluid, effusions, cytomorphology, metastatic carcinoma |
| Cite Article: | "CYTOMORPHOLOGY OF METASTATIC SQUAMOUS CELL CARCINOMA IN EFFUSIONS; A RETROSPECTIVE STUDY", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.9, Issue 5, page no.597 - 604, May-2024, Available :http://www.ijrti.org/papers/IJRTI2405083.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2405083
Registration ID:189937
Published In: Volume 9 Issue 5, May-2024
DOI (Digital Object Identifier):
Page No: 597 - 604 Country: Puducherry, Puducherry, India, India Research Area: Health Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2405083 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2405083 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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