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The inflammatory skin condition known as psoriasis is a chronic immune-mediated condition marked by keratinocyte hyperproliferation and a number of systemic comorbidities. With an emphasis on recent developments in our knowledge of the functions of particular immune cells and cytokines in the onset and maintenance of disease, we examine the intricate interactions between genetic, environmental, and immunological factors that contribute to its pathogenesis. There is a thorough discussion of the clinical signs and symptoms of psoriasis, which include guttate, inverted, pustular, and erythrodermic psoriasis, as well as localized plaque psoriasis. Topical treatments (corticosteroids, vitamin D analogs, retinoids), phototherapy (UVB, PUVA), traditional systemic therapies (methotrexate, cyclosporine), and the growing number of biologic agents that target particular immune pathways (TNF-α inhibitors, IL-17 inhibitors, IL-12/23 inhibitors, and IL-23 inhibitors) are also critically evaluated in this review. In addition, we discuss new therapeutic developments and individualized treatment plans based on patient characteristics, phenotype, and disease severity. This emphasizes the value of a multidisciplinary approach for the best possible management of psoriasis and better patient results.
Keywords:
Interleukin inhibitor
Cite Article:
"Psoriasis : A Comprehensive Review of Current and Emerging Therapies", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 1, page no.a90-a107, January-2025, Available :http://www.ijrti.org/papers/IJRTI2501017.pdf
Downloads:
000432
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator