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Background:
Tinea infections have become increasingly prevalent, with a rise in chronic, recurrent, and treatment-resistant cases. Conventional antifungal therapies often fail due to drug resistance mechanisms, necessitating alternative approaches. Given that dermatophytes reside in the stratum corneum, superficial peeling with salicylic acid may aid in fungal removal.
Aim:
To evaluate the efficacy of a 35% salicylic acid peel in treating tinea infections.
Methods:
A total of 40 patients with KOH-positive tinea infections were included. Exclusion criteria comprised extensive body involvement, tinea facei/capitis, pregnancy, and concomitant infections. A 35% salicylic acid solution was applied weekly for four weeks. No systemic or topical antifungals were used. KOH tests were repeated one week after the final session to assess fungal presence.
Results:
Out of 40 patients, 22 (55%) showed negative KOH findings post-treatment, though 7 experienced recurrences. Among 15 patients with prior antifungal resistance, 12 responded positively to salicylic acid therapy. Common side effects included a transient burning sensation.
Conclusion:
Salicylic acid peel effectively removes dermatophytes by exfoliating the stratum corneum, making it a cost-effective alternative for resistant cases. Since it does not act directly on fungi, there is no risk of inducing resistance. However, treatment duration may need optimization to minimize recurrence.
Keywords:
Tinea, Dermatophytes, Salicylic Acid, Antifungal Resistance, Chemical Peel.
Cite Article:
"Efficacy of 35% Salicylic Acid Peel in Tinea Infections: A Novel Approach", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 5, page no.b498-b502, May-2025, Available :http://www.ijrti.org/papers/IJRTI2503173.pdf
Downloads:
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator