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Artificial Intelligence (AI) is reshaping natural product drug discovery, offering a transformative approach to an historically intricate process. Divided into machine learning and deep learning, AI accelerates the identification of therapeutic compounds from diverse natural sources. While machine learning employs algorithms like SVM, RF, and Bayesian Networks, deep learning, using neural networks, excels in image and sequence analysis. Traditional natural product discovery involves a multistep process, facing challenges such as biodiversity loss, complex structures, and resource-intensive procedures. AI addresses these challenges by optimizing processes, enhancing reproducibility, and accelerating advancements in the field. Despite challenges like limited datasets and ethical considerations, AI in natural product discovery is applied for virtual screening, predicting pharmacokinetics, toxicity forecasting, ensuring quality control, overcoming resource constraints, and integrating multi-omics data. The future of AI in natural product discovery holds promise with advancements in predictive modeling, generative models, knowledge graphs, explainable AI, automation, personalized medicine, and collaborative data sharing. Ethical considerations emphasize equitable data ownership, bias mitigation, traditional knowledge respect, transparency, privacy protection, and collaborative, culturally sensitive approaches. In conclusion, the vast potential of AI in natural product drug discovery positions it to become a mainstream force in the future, promising transformative advancements for the development of novel therapeutics.
Keywords:
Artificial Intelligence, machine learning, deep learning, network, natural product, drug discovery
Cite Article:
"Unleashing the Power of AI in Natural Product Discovery", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 4, page no.b722-b733, April-2025, Available :http://www.ijrti.org/papers/IJRTI2504191.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator