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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21686
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| Paper Title: | ADVANCES IN OPHTHALMIC GEL SYSTEMS FOR ENHANCED DELIVERY: A REVIEW OF FORMULATION STRATEGIES AND THERAPEUTIC EFFICACY |
| Authors Name: | JAYESH SANDIP SAWARKAR , Dr. JITENDRA SHINDE |
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IJRTI_203332
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| Published Paper Id: | IJRTI2505007 |
| Published In: | Volume 10 Issue 5, May-2025 |
| DOI: | |
| Abstract: | Ocular drug delivery remains a significant therapeutic challenge due to the eye's complex anatomy and protective physiological mechanisms, such as tear drainage, blinking, and the corneal barrier. Due to their low bioavailability, traditional eye drops need frequent dosage, which frequently leads to poor patient compliance. Hydrogel-based ophthalmic gels have become a viable substitute in recent years, providing better therapeutic effectiveness, controlled drug release, and prolonged ocular residency. These gels can gel in situ after delivery because they are made of biocompatible polymers that react to environmental cues like pH and temperature. Their mucoadhesive properties improve absorption by keeping the medication on the eye surface. Achieving the ideal viscosity, drug stability, sanitation, and restricted drug loading capacity are still obstacles, though. Notwithstanding these obstacles, developments in formulation techniques and polymer research are spurring innovation in this area. Furthermore, the review integrates findings from recent literature to evaluate current advances and limitations in gel-based ocular delivery. |
| Keywords: | Keywords: Ocular drug delivery, hydrogel-based gels, ophthalmic formulations, controlled release, biocompatible polymers |
| Cite Article: | "ADVANCES IN OPHTHALMIC GEL SYSTEMS FOR ENHANCED DELIVERY: A REVIEW OF FORMULATION STRATEGIES AND THERAPEUTIC EFFICACY", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 5, page no.a51-a60, May-2025, Available :http://www.ijrti.org/papers/IJRTI2505007.pdf |
| Downloads: | 000380 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2505007
Registration ID:203332
Published In: Volume 10 Issue 5, May-2025
DOI (Digital Object Identifier):
Page No: a51-a60 Country: Akola, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2505007 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2505007 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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