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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21686
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Total Authors : 22487
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Total Countries : 159
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| Paper Title: | Vitamin B12 and Its Multifaceted Role in Human Health: A Comprehensive Review |
| Authors Name: | Ankita Vala , Krunal Chudasama |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_203183
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| Published Paper Id: | IJRTI2505036 |
| Published In: | Volume 10 Issue 5, May-2025 |
| DOI: | |
| Abstract: | Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a vital role in numerous physiological functions, including red blood cell formation, neurological function, DNA synthesis, and energy metabolism. Despite its essential nature, the human body cannot synthesize Vitamin B12 and must rely on dietary intake or supplementation. This review explores the biochemical structure, absorption mechanisms, dietary sources, and diverse functions of Vitamin B12 in maintaining human health. Particular attention is given to the complex absorption process involving intrinsic factor, its storage in the liver, and the clinical implications of deficiency, which can lead to megaloblastic anemia and irreversible neurological damage. The review also examines risk factors for deficiency, including dietary restrictions, gastrointestinal disorders, and aging. Furthermore, it discusses diagnostic markers, therapeutic approaches, and current research highlighting emerging roles of Vitamin B12 in cardiovascular health, cognitive function, and mood regulation. Understanding the multifaceted role of Vitamin B12 is crucial for effective prevention, diagnosis, and treatment of related disorders, as well as for guiding future nutritional and medical research. |
| Keywords: | Vitamin B12, Cobalamin, B12 Deficiency, Vitamin B12 Absorption, Homocysteine Metabolism, Vitamin B12 Metabolism, Neurological Health, Cognitive Function, Vitamin B12 Supplementation, Homocysteine Metabolism, B12 Biomarkers. |
| Cite Article: | "Vitamin B12 and Its Multifaceted Role in Human Health: A Comprehensive Review", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 5, page no.a365-a371, May-2025, Available :http://www.ijrti.org/papers/IJRTI2505036.pdf |
| Downloads: | 000500 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2505036
Registration ID:203183
Published In: Volume 10 Issue 5, May-2025
DOI (Digital Object Identifier):
Page No: a365-a371 Country: Bhavnagar, Gujarat, India Research Area: Health Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2505036 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2505036 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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