Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
Alzheimer’s drug discovery was so far constrained to focusing on well-studied
therapeutic hypotheses. A more diverse, systems-integrated approach may un
cover new therapeutic hypotheses based on the heterogeneity of AD processes and
the requirement for understudied protein targets and biological mechanisms. Tar
get enabling packages are the development of high quality experimental reagents
and informatic outputs and would accelerate the rapid evaluation of new emerging
systems-integrated targets in AD. Drug discovery has witnessed dramatic change
recently. Many AI/ML technologies have been applied in the recent past. The
enhanced nature of these models has led to a growing need for transparency and
interpretability. In this paper, we make a review of the XAI approach, which pro
vides a novel means to achieve this goal for a more interpretable understanding of
machine learning predictions to improve the classification performance of a prob
lem by overcoming the limitations of traditional statistical models and conventional
machine learning techniques in handling complex molecular datasets. To do this,
a dataset of 7298 compounds extracted from the ChEMBL database along with
molecular descriptors were used.
Keywords:
Alzheimer’s disease, drug development, drug targets
Cite Article:
"Drug Discovery Research Paper: Using Machine Learning", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 5, page no.b123-b127, May-2025, Available :http://www.ijrti.org/papers/IJRTI2505117.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator