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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21664
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| Paper Title: | Formulation Method Development And Validation Of Active Pharmaceutical Ingredient in Tablet Dosage Form |
| Authors Name: | Pranjali Vilas Shandilya , S.G.Jawarkar |
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IJRTI_204990
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| Published Paper Id: | IJRTI2506188 |
| Published In: | Volume 10 Issue 6, June-2025 |
| DOI: | |
| Abstract: | Abstract: Rapid and accurate HPLC method has been developed for the simultaneous estimation of Meloxicam and Rizatriptan in tablet dosage form. Chromatographic separation of both anti-inflammatory drugs was achieved on a Zodiac-100 C18 (150 × 4.6 mm ID, 5 µm) using a mobile phase consisting of 760 mL methanol and 240 mL of buffer (0.2% ammonium acetate in water), at a flow rate of 1.0 mL/min. Detection was carried out at 245 nm. The separation was achieved in less than 10 minutes. The method was validated as per ICH guidelines for parameters including linearity, accuracy, precision, system suitability, specificity, robustness, limit of detection (LOD), limit of quantitation (LOQ), and range. Linearity, accuracy, and precision were found to be within acceptable limits over the range of 0.5–3.0 µg/mL for Meloxicam and 5–30 µg/mL for Rizatriptan. The method proved to be sensitive, specific, and suitable for routine quality control of these drugs in pharmaceutical formulations. |
| Keywords: | Keywords: High-Performance Liquid Chromatography, Meloxicam, Rizatriptan, Anti-inflammatory drugs, pharmaceutical formulation, Method validation. |
| Cite Article: | "Formulation Method Development And Validation Of Active Pharmaceutical Ingredient in Tablet Dosage Form", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 6, page no.b733-b740, June-2025, Available :http://www.ijrti.org/papers/IJRTI2506188.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2506188
Registration ID:204990
Published In: Volume 10 Issue 6, June-2025
DOI (Digital Object Identifier):
Page No: b733-b740 Country: Nagpur , Maharashtra , India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2506188 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2506188 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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