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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | "RECENT ADVANCES IN SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF NANO SIZED SCHIFF BASE AMINO ACID CU(II) COMPLEXES." |
| Authors Name: | Kirti Salame , Dr. Arun Singh |
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IJRTI_205720
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| Published Paper Id: | IJRTI2508062 |
| Published In: | Volume 10 Issue 8, August-2025 |
| DOI: | |
| Abstract: | The Alpha-amino acids Azomethine amino ligands were created by combining L-phenylalanine (P) and DL-tryptophan (T) with 3-methoxysalicylaldehyde (MS) or 4-diethylamino salicylaldehyde (DS). We checked the infrared, 1H, and 13C nuclear magnetic resonance, as well as the melting temperature, for every ligand. Fe (II) and Cu (II) complexes with novel nanoscale structures were generated when the azomethine amino ligands were combined with metal salts. In a dynamic air environment, the separated complexes were studied using thermal analysis (TGA), infrared spectra, ultraviolet-visible spectra, and elemental analysis. From the thermal data, the kinetic and Redfern parameters were calculated. A lack of electrolysis is supported by the low molar conductance values of the complexes. According to the results of the magnetic susceptibility experiments, the complexes under study are paramagnetic. Additionally, spectrophotometric determinations of the produced complexes' stability constants were made. The analytical findings show that amino acid Schiff bases coordinate with Fe (II) and Cu (II) ions in octahedral geometry, according to the general formula [M(HL)2]. and act as dibasic tridentate ONO ligands. liquid water. Using transmission electron microscopy, the size of the produced complexes' particles was measured and found to be nanoscale. Additionally, against some bacteria (+ve), The ligands and their complexes were evaluated for their antibacterial activity against Escherichia coli (-ve) and Micrococcus luteus (+ve), as well as fungi (+ve) such Aspergillus Niger, Candida glabrata, and Saccharomyces cerevisiae. Metal complexes, according to these investigations, are more effective against bacteria and fungi than their equivalent ligands. Through the use of spectrum investigations, viscosity tests, and gel electrophoreses, seeing the complexes' interaction with CT-DNA. The fact that the produced complexes may potentially intercalate with DNA was also uncovered. |
| Keywords: | Azomethine, Amino acid, TGA, TEM, Antimicrobial, DNA interaction |
| Cite Article: | ""RECENT ADVANCES IN SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF NANO SIZED SCHIFF BASE AMINO ACID CU(II) COMPLEXES."", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 8, page no.a516-a523, August-2025, Available :http://www.ijrti.org/papers/IJRTI2508062.pdf |
| Downloads: | 000786 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2508062
Registration ID:205720
Published In: Volume 10 Issue 8, August-2025
DOI (Digital Object Identifier):
Page No: a516-a523 Country: Multai, Madhya Pradesh, India Research Area: Chemistry Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2508062 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2508062 |
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ISSN: 2456-3315
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