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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21504
Article Published : 8513
Total Authors : 22399
Total Reviewer : 805
Total Countries : 158
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| Paper Title: | Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method |
| Authors Name: | Pranali Gajanan Ravekar , S. G.Jawarkar |
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IJRTI_205258
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| Published Paper Id: | IJRTI2508074 |
| Published In: | Volume 10 Issue 8, August-2025 |
| DOI: | |
| Abstract: | A simple, specific and sensitive reverse phase high performance liquid chromatographic method was developed and validated for simultaneous determination of vonoprazan and amoxicillin from pharmaceutical dosage forms. The method uses Hypersil, C18 (250mm x 4.6ID, Particle size: 5 um) column and isocratic elution. The mobile phase composed of MeOH:Water:Glacial acetic acid, at the ratio of 75:24.5:0.5 v/v was used at a flow rate of 1.0 ml /min. UV detector was programmed at 232 nm for first 10 min and at 244 nm for 10 to 20 min. All the validation parameters were in acceptable range. The developed method was effectively applied to quantitate amount of vonoprazan and amoxicillin from tablets. The method was also applied suitably for determining the degradation products of vonoprazan and amoxicillin . |
| Keywords: | Vonoprazan, reverse phase high performance liquid chromatography, amoxicillin analysis, tablets |
| Cite Article: | "Analytical method developemtn and validation for simultaneous estimation of API in pharmaceutical dosage form by using RP-HPLC method", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 8, page no.a600-a609, August-2025, Available :http://www.ijrti.org/papers/IJRTI2508074.pdf |
| Downloads: | 000923 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2508074
Registration ID:205258
Published In: Volume 10 Issue 8, August-2025
DOI (Digital Object Identifier):
Page No: a600-a609 Country: amravati, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2508074 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2508074 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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