 |
International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
|
Issue: March 2026
Volume 11 | Issue 3
Review Result and Publication of Paper within : 2-3 days
Click Here For more DetailsFor Authors
Forms / Download
Published Issue Details
Editorial Board
Other IMP Links
Facts & Figure
Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21574
Article Published : 8528
Total Authors : 22430
Total Reviewer : 805
Total Countries : 159
Indexing Partner
Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
Published Paper Details
|
|
| Paper Title: | Nanogel based drug delivery system for the treatment of vitiligo; systemic review |
| Authors Name: | Sayali More , Sakshi Devkar , Anushka Patil , Shruti Alasandkar , Shailaja Kamble |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_207485
|
| Published Paper Id: | IJRTI2511080 |
| Published In: | Volume 10 Issue 11, November-2025 |
| DOI: | |
| Abstract: | Vitiligo is a chronic, non-congenital skin disorder characterized by the loss of melanocytes, leading to white patches predominantly on sun-exposed areas such as the face, neck, and arms. Affecting approximately 0.5–1% of the population, it often presents symmetrically and tends to run in families, suggesting a polygenic inheritance pattern. The exact cause remains unclear, but several hypotheses have been proposed, including autoimmune destruction of melanocytes, oxidative stress, and genetic predisposition involving immune-related genes such as HLA and CTLA-4. Clinically, vitiligo manifests in segmental, non-segmental, and mixed forms, with non-segmental being the most prevalent. Immune-mediated mechanisms involving T cells, antigen-presenting cells, and inflammatory cytokines like IFN-γ and TNF-α play a central role in melanocyte damage. Treatment aims to restore pigmentation and includes topical corticosteroids, phototherapy, laser therapy, and in some cases, melanocyte transplantation. However, therapeutic success is limited due to the complex etiology. Emerging technologies such as nanogels offer promising drug delivery platforms for targeted therapy. Nanogels are nanoscale, highly absorbent polymeric networks capable of encapsulating drugs through various interactions. Their stability, biocompatibility, and modifiable surfaces make them suitable for delivering bioactive molecules, particularly in protein and gene therapy. Various fabrication methods, including emulsion techniques and self-assembly, support their development for clinical use in treating vitiligo. |
| Keywords: | vitiligo, treatment, nanogel, melanocytes, depigmentation, |
| Cite Article: | "Nanogel based drug delivery system for the treatment of vitiligo; systemic review", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 11, page no.a674-a692, November-2025, Available :http://www.ijrti.org/papers/IJRTI2511080.pdf |
| Downloads: | 000200 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
| Publication Details: |
Published Paper ID: IJRTI2511080
Registration ID:207485
Published In: Volume 10 Issue 11, November-2025
DOI (Digital Object Identifier):
Page No: a674-a692 Country: Sangali , Maharashtra , India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2511080 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2511080 |
| Share Article: | |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijrti.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
ISSN Details
 |
 |
|
ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
DOI (A digital object identifier)
| Providing A digital object identifier by DOI.ONE How to Get DOI? |
Conference
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Important Details
Join RMS/Earn 300
WhatsApp
Click Here
Click Here
Indexing Partner |
|||
| Copyright © 2026 - All Rights Reserved - IJRTI | |||