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Background: Chronic kidney disease (CKD) is strongly associated with cardiovascular morbidity and mortality. Cardiorenal interactions lead to structural and functional cardiac abnormalities, including left ventricular hypertrophy (LVH), systolic dysfunction, diastolic dysfunction, arrhythmias, and valvular disease. Early identification of cardiac involvement in CKD is essential to reduce adverse outcomes..
Aim: To evaluate the cardiac abnormalities in patients of chronic kidney disease..
Objective:
• To evaluate cardiac abnormalities in patients with CKD (Stage 3 and above) and determine their patterns using ECG and 2D echocardiography.
• To document the cardiac abnormalities among patients admitted with chronic kidney disease.
• To evaluate types of cardiac abnormalities in chronic kidney disease.
Materials and Methods: A cross-sectional study was conducted in the Department of Medicine, Rohilkhand Medical College & Hospital, Bareilly, between August 2023 and December 2024. Seventy-six adult CKD patients (≥18 years) fulfilling inclusion criteria were evaluated. Demographic data, clinical profile, comorbidities, biochemical parameters, ECG, and 2D echocardiography were recorded. Statistical analysis was performed using SPSS v25. A p-value <0.05 was considered significant.
Results
Among 76 patients, males were 56.6% and the most common age group was 35–44 years. Hypertension (55.3%), diabetes (30.3%), and smoking (35.5%) were frequent comorbidities. Proteinuria ≥1+ was present in 84.2%. Mean urea and creatinine levels were 176.9 ± 72.3 mg/dl and 8.7 ± 4.1 mg/dl, respectively.
ECG abnormalities: LVH was the most common (48.7%), followed by poor R-wave progression (6.6%) and ST-elevation (5.3%).
Echocardiographic abnormalities: Diastolic dysfunction (Grade I–III) and LVH were predominant. Cardiorenal syndrome (CRS) type 4 was the most prevalent subtype.
Conclusion:
Cardiac abnormalities are highly prevalent in CKD patients, even before the onset of overt cardiac symptoms. LVH, diastolic dysfunction, and CRS type 4 are the most frequent findings. Routine ECG and echocardiographic evaluation should be incorporated into CKD management for early detection and timely intervention.
": “Evaluation of Cardiac Abnormalities in Chronic Kidney Disease.”-A Cross Sectional Study.", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 12, page no.a102-a115, December-2025, Available :http://www.ijrti.org/papers/IJRTI2512015.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator