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Oral fast dissolving films (ofdfs) are innovative drug delivery systems that rapidly disintegrate when placed on the tongue, eliminating the need for water. They provide a convenient alternative to tablets and capsules, particularly for children, elderly patients, and individuals with swallowing difficulties. Ofdfs enable quick therapeutic action, improved patient adherence, and easy portability, making them suitable for medications such as antiemetics, analgesics, and antiallergics. This review discusses the historical development, formulation approaches, manufacturing techniques, evaluation methods, marketed products, and recent advancements in ofdfs. Special focus is given to excipient selection, drug loading criteria, and modern technologies including electrospinning and 3D printing. Challenges like limited drug loading, taste masking, and moisture sensitivity are highlighted. Current trends aim at personalized therapies, biologics delivery, and continuous manufacturing, indicating that ofdfs are likely to become a widely accepted patient-centered dosage form.
Keywords:
ORAL FAST DISSOLVING FILMS: A DETAILED REVIEW
Cite Article:
"ORAL FAST DISSOLVING FILMS: A DETAILED REVIEW", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 12, page no.b549-b558, December-2025, Available :http://www.ijrti.org/papers/IJRTI2512163.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator