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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: March 2026
Volume 11 | Issue 3
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Impact Factor : 8.14
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Issue Published : 118
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| Paper Title: | In-Vitro Anthelmintic Activity of Formulated Syrup from Ocimum basilicum (Sweet Basil) Leaves Ethanolic Extract Against Ascaris suum |
| Authors Name: | Reysa Raphaelle Gabilagon , Merry Joy Barrios , Joana Patrice Aldea , Hans Aedrian Lantin , Fairy Girl Bolanio |
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IJRTI_209159
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| Published Paper Id: | IJRTI2601118 |
| Published In: | Volume 11 Issue 1, January-2026 |
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| Abstract: | Ascarias, caused by either Ascaris suum and Ascaris lumbricoides, is one of the most prevalent and most neglected tropical diseases (NTDs) in the world. In this study, the researchers assessed the anthelmintic capability of Ocimum basilicum (Sweet Basil) in attempt to combat ascariasis. This utilized true experimental research design, specifically pretest-posttest control group method. Using logarithmic scale method, the approximate effective concentration (AEC) of the O. basilicum (Sweet Basil) leaves ethanolic extract was determined. Three concentrations (3.98%, 15.84% and 63.06%) used have shown effectivity in paralyzing A. suum. The AEC used in formulating medicated syrup was 3.98% (1.99mL). The formulated syrup was assayed and its density, viscosity, and pH were identified as 1.26g/mL, 0.29cp, and 5, respectively. Moreover, in the in vitro anthelmintic assay, three treatment groups were utilized mainly pyrantel pamoate (positive control), formulated syrup from O. basilicum (Sweet Basil) leaves ethanolic extract (experimental group), and distilled water (negative control). A total of 45 A. suum roundworms were used, divided into three groups, each group had three trials, comprising of five test subjects in each trial. The percentage paralysis index of each treatment group was calculated in accordance to 1-hour and 3-hour post treatment. The formulated syrup from Ocimum basilicum showed 100% paralysis index, which means that it has the ability to induce paralysis to the helminth. Its action was comparable to the action of pyrantel pamoate against the Ascaris suum. Hence, it can be a potential anthelmintic agent. |
| Keywords: | Ocimum basilicum, Ascaris suum, Pyrantel pamoate, anthelmintic |
| Cite Article: | "In-Vitro Anthelmintic Activity of Formulated Syrup from Ocimum basilicum (Sweet Basil) Leaves Ethanolic Extract Against Ascaris suum", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.11, Issue 1, page no.b133-b138, January-2026, Available :http://www.ijrti.org/papers/IJRTI2601118.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2601118
Registration ID:209159
Published In: Volume 11 Issue 1, January-2026
DOI (Digital Object Identifier):
Page No: b133-b138 Country: General Santos City, South Cotabato, Philippines Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2601118 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2601118 |
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ISSN: 2456-3315
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