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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: April 2026
Volume 11 | Issue 4
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Impact Factor : 8.14
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| Paper Title: | A COMPREHENSIVE REVIEW ON ADVANCEMENTS IN TADALAFIL FORMULATION AND TRANSDERMAL DELIVERY (1) |
| Authors Name: | HARSHAL BHAGWAN PATIL , Mohammed Awais , Shaikh Habiburrahman , Momin Sanaurrehman , Mrunal Shirsat |
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IJRTI_211198
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| Published Paper Id: | IJRTI2604199 |
| Published In: | Volume 11 Issue 4, April-2026 |
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| Abstract: | Consequently, the developments in transdermal delivery systems for Tadalafil are a shift in the management of erectile dysfunction and benign prostatic hyperplasia. The main disadvantages of conventional oral formulations are poor absorption, first-pass metabolism, and a number of side effects that may compromise patient compliance. Nonetheless, there are drawbacks associated with these formulation types, which have been overcome to a large extent by transdermal formulations such as patches and formulations at the nano scale Further, the slow and sustained release typical of transdermal delivery has been linked to lessened system toxicities, thus improving patient compliance. It has also reduced the bioavailability and steady state drug concentrations than that of transdermal Tadalafil, which increases the therapeutic efficacy. Research work has also started to support these innovations and the potential of the transdermal Tadalafil in offering better results than the oral Tadalafil has been proved. Further studies are being conducted on the ways to improve the efficiency of Tadalafil administration, and all of them show a positive trend in this regard. Subsequent studies will also be required to determine uniform transdermal formulations and elaborate on therapeutic possibilities in uncommon patient groups. As the methods of transdermal drug delivery develop all over the world, the possibility to enhance the usage of Tadalafil for patients can be seen. This shift is not only expected to increase the effectiveness of therapy but also to increase the general quality of life of patients. Transdermal Tadalafil can be considered a new moving step in the search for which the most adequate therapeutic solution for erectile dysfunction may exist |
| Keywords: | Tadalafil, Delivery system, Oral Bioavailability, Nano-formulations |
| Cite Article: | "A COMPREHENSIVE REVIEW ON ADVANCEMENTS IN TADALAFIL FORMULATION AND TRANSDERMAL DELIVERY (1)", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.11, Issue 4, page no.b463-b471, April-2026, Available :http://www.ijrti.org/papers/IJRTI2604199.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2604199
Registration ID:211198
Published In: Volume 11 Issue 4, April-2026
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Page No: b463-b471 Country: Thane, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2604199 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2604199 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
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