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Paper Title:
Phytochemical Isolation, Structural Characterization, and Mechanistic Evaluation of Bioactive Constituents from Leaves of Moringa oleifera Exhibiting Antiulcer Activity
Peptic ulcer disease continues to be one of the most common diseases of the digestive system, afflicting millions of people yearly. The pathogenesis of peptic ulcer disease results from a disparity between aggressive elements, such as gastric acid secretion, oxidative stress, inflammation, and microorganisms like Helicobacter pylori, and defensive factors such as mucus secretion, prostaglandins, and antioxidative defenses. Despite the efficacy of pharmacologic treatment using proton pump inhibitors, histamine H2 receptor blockers, and mucosal defense medications, the long-term use of these therapies has been linked to various side effects, including acid rebound, drug resistance, and infection.
As a result, medicinal plants are now considered excellent sources of gastroprotective substances due to their high phytochemical content and multitarget pharmacological functions. Moringa oleifera Lam., popularly referred to as the drumstick tree, is a widespread medicinal herb from the Moringaceae family. Moringa oleifera contains several secondary metabolite groups, including flavonoids, phenolic acids, alkaloids, saponins, tannins, glycosides, glucosinolates, and phytosterols. These substances have considerable antioxidant, anti-inflammatory, antimicrobial, and cell protective properties that contribute to the gastrointestinal tract's safeguarding.
"Phytochemical Isolation, Structural Characterization, and Mechanistic Evaluation of Bioactive Constituents from Leaves of Moringa oleifera Exhibiting Antiulcer Activity", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.11, Issue 5, page no.a740-a752, May-2026, Available :http://www.ijrti.org/papers/IJRTI2605092.pdf
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator