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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: June 2026
Volume 11 | Issue 6
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 121
Article Submitted : 24719
Article Published : 9358
Total Authors : 24865
Total Reviewer : 861
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| Paper Title: | Antimicrobial activity of newly synthesized Dehydrozingerone compound |
| Authors Name: | Neelakanth.M.Jeedi , Anupama S Gaonkar , Dhanya Holla K , Karunya Benake , Pradeepgouda Hiralingannavar |
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IJRTI_213075
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| Published Paper Id: | IJRTI2605179 |
| Published In: | Volume 11 Issue 5, May-2026 |
| DOI: | |
| Abstract: | Background: The continuous rise of antimicrobial resistance underscores the urgent need to discover and develop novel antimicrobial agents. Objective; This investigation aims to characterize the antimicrobial profile of Dehydrozingerone by systematically assessing its efficacy against selected bacterial and fungal pathogens. Materials & Methods; The antimicrobial potency of Dehydrozingerone was evaluated by determining both the Minimum Inhibitory Concentration via the broth serial dilution technique and the Zone of Inhibition using the agar well diffusion assay. Testing was conducted against bacterial strains (Staphylococcus aureus and Escherichia coli) as well as fungal cultures (Aspergillus niger and Candida albicans). Organisms were sub cultured and incubated in Mueller-Hinton Broth under optimized conditions. Following incubation, culture dynamics were assessed to establish the lowest concentration required to suppress visible microbial growth, where a lower MIC value denotes superior therapeutic efficacy. Additionally, the ZOI was quantified by measuring the clear diameter of growth inhibition surrounding the diffusion wells. Results; Dehydrozingerone exhibited substantial inhibitory activity against all tested bacterial and fungal strains. The quantitative data gathered from both the MIC and ZOI assays highlight its prospective utility as a plant-derived antimicrobial candidate for future therapeutic interventions. Conclusion; The findings of this study demonstrate that Dehydrozingerone possesses potent antimicrobial attributes, establishing it as a promising lead compound for the design and development of next-generation therapeutic agents. |
| Keywords: | Escherichia coli, Staphylococcus aureus, Candida albicans, Aspergillus niger, Minimum Inhibitory Concentration. |
| Cite Article: | "Antimicrobial activity of newly synthesized Dehydrozingerone compound", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2456-3315, Vol.11, Issue 5, page no.b681-b693, May-2026, Available :http://www.ijrti.org/papers/IJRTI2605179.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2605179
Registration ID:213075
Published In: Volume 11 Issue 5, May-2026
DOI (Digital Object Identifier):
Page No: b681-b693 Country: Hubballi,, Karnataka, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2605179 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2605179 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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