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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

Issue per Year : 12

Volume Published : 7

Issue Published : 75

Article Submitted : 4262

Article Published : 2397

Total Authors : 6316

Total Reviewer : 532

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Paper Title: Thermal Sintering: A Novel technique in Formulation of Controlled Release Dosage form
Authors Name: Dr.K.V.Ratnamala , P.Madhuri
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IJRTI_181373
Published Paper Id: IJRTI2010008
Published In: Volume 5 Issue 10, October-2020
DOI:
Abstract: Sintering is defined as the thermal treatment of a powder or compact at a temperature below the melting point of the main constituent, for the purpose of increasing its strength by bonding together of particles. The sintering concept in pharmaceutical science is relatively recent, but research interests relating to this process have been growing. Sintering has been described as the mechanism for the strengthening of the mechanical properties of consolidated pharmaceutical powders at elevated temperatures, for solid-bond formation during tablet compression, and for thermal curing of polymer-latex film -Coatings. The changes in the microstructures, Hardness, Friability, Wettability, disintegration time and dissolution rate of tablets stored at elevated temperature were also described as a result of sintering. Controlled release oral dosage forms were developed by sintering the polymer matrix by exposing to temperature above glass transition (Tg) point of the polymer. In the application of thermal sintering technique to the formulation of controlled release dosage form, the main research focus has been on the influence of sintering on the alteration of the microstructures in a polymeric matrix and the release of the active ingredients from the matrix. KEYWORDS: Thermal sintering, Glass transition point, Controlled release, Matrix tablets
Keywords: Thermal sintering, Glass transition point, Controlled release, Matrix tablets
Cite Article: "Thermal Sintering: A Novel technique in Formulation of Controlled Release Dosage form", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.5, Issue 10, page no.38 - 45, October-2020, Available :http://www.ijrti.org/papers/IJRTI2010008.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2010008
Registration ID:181373
Published In: Volume 5 Issue 10, October-2020
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Page No: 38 - 45
Country: hyderabad, telangana, India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2010008
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2010008
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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