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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21504
Article Published : 8513
Total Authors : 22399
Total Reviewer : 805
Total Countries : 158
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| Paper Title: | Review on Recent Advances in In-Situ Gel: Drug Delivery System for Nasal and Various Routes |
| Authors Name: | Vinayak A Katekar , Om P Bhurbhure , Sarita R Bawankule , Milind J Umekar |
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IJRTI_182208
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| Published Paper Id: | IJRTI2206007 |
| Published In: | Volume 7 Issue 6, June-2022 |
| DOI: | |
| Abstract: | The study was conducted to explore in depth the in-situ gel nasal drug delivery system since these systems have higher systemic bioavailability via the nose route as compared to the oral route of administration. Many medications now have higher systemic absorption via the nasal route as compared to oral administration. The nose is also seen to be an appealing route for needle-free immunisation and systemic medication administration, particularly when quick absorption and action are required. Because of the high permeability of the nasal epithelium, fast drug absorption through this membrane, and avidity of first pass metabolism, nasal delivery is a viable alternative to oral or parenteral administration for several drugs. The study was conducted to explore in depth the in-situ gel nasal drug delivery system since these systems have higher systemic bioavailability via the nose route as compared to the oral route of administration. Many medications now have higher systemic absorption via the nasal route as compared to oral administration. The nose is also seen to be an appealing route for needle-free immunisation and systemic medication administration, particularly when quick absorption and action are required. Because of the high permeability of the nasal epithelium, fast drug absorption through this membrane, and avidity of first pass metabolism, nasal delivery is a viable alternative to oral or parenteral administration for several drugs. |
| Keywords: | In-situ gel, nasal mucosa, Bioavailability, novel dosage form, first pass metabolism |
| Cite Article: | "Review on Recent Advances in In-Situ Gel: Drug Delivery System for Nasal and Various Routes", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 6, page no.32 - 42, June-2022, Available :http://www.ijrti.org/papers/IJRTI2206007.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2206007
Registration ID:182208
Published In: Volume 7 Issue 6, June-2022
DOI (Digital Object Identifier):
Page No: 32 - 42 Country: -, -, - Research Area: Engineering Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2206007 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2206007 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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