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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21504
Article Published : 8513
Total Authors : 22399
Total Reviewer : 805
Total Countries : 158
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| Paper Title: | A review on Drug discovery and development in the last year 2020-21 for the corona virus |
| Authors Name: | Manjusha Balakrishna Suryawanshi , Swati Rajendra Sonawane , Mohini Arun Pagar , Sonali D Deo |
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IJRTI_182511
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| Published Paper Id: | IJRTI2206173 |
| Published In: | Volume 7 Issue 6, June-2022 |
| DOI: | |
| Abstract: | The COVID-19 pandemic caused by SARS-CoV-2 infection is spreading at an alarming rate and has created an unprecedented health emergency around the globe. The development of antiviral agents was an urgent priority. Biochemical events critical to the corona virus replication cycle provided a number of attractive targets for drug development. These include, spike protein for binding to host cell-surface receptors, proteolytic enzymes that are essential for processing poly proteins into mature viruses, and RNA-dependent RNA polymerase for RNA replication. There has been a lot of ground work for drug discovery and development against these targets. Also, high throughput screening efforts have led to the identification of diverse lead structures, including natural product-derived molecules. This review highlights past and present drug discovery and medicinal-chemistry approaches against SARS CoV and COVID-19 targets. The review hopes to stimulate further research and will be a useful guide to the development of effective therapies against COVID-19 and other pathogenic corona virtues |
| Keywords: | antiviral agents, COVID-19, drug discovery |
| Cite Article: | "A review on Drug discovery and development in the last year 2020-21 for the corona virus", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 6, page no.1082 - 1100, June-2022, Available :http://www.ijrti.org/papers/IJRTI2206173.pdf |
| Downloads: | 000205275 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2206173
Registration ID:182511
Published In: Volume 7 Issue 6, June-2022
DOI (Digital Object Identifier):
Page No: 1082 - 1100 Country: Nashik, Maharashtra, India Research Area: Chemistry Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2206173 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2206173 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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