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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21504
Article Published : 8513
Total Authors : 22399
Total Reviewer : 805
Total Countries : 158
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| Paper Title: | A Review on Solubility Enhancement of Water Insoluble Drugs by Various Techniques |
| Authors Name: | Dr. N.Madhavi , Varsha , Shivani , Praneeth |
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| Author Reg. ID: |
IJRTI_182488
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| Published Paper Id: | IJRTI2206180 |
| Published In: | Volume 7 Issue 6, June-2022 |
| DOI: | |
| Abstract: | Aim of the current study is to improve the solubility and oral bioavailability of poorly water-soluble drugs. Solid dispersions, one of the technique to improve the solubility and oral bioavailability of poorly soluble drugs. Solid dispersions are mainly prepared for BCS class -II drugs as these drugs have low solubility and high permeability. Solid dispersion can be prepared by various methods which includes Kneading method, Melting method, Solvent method, Electrospinning etc., The present article mainly focuses on various available methods to improve the drug solubility. The water-soluble carriers are used in preparation of solid dispersions which increases the dissolution rate of poorly soluble drug. The carrier selection should be freely soluble in water, pharmacologically inert and possess high dissolution rate. Examples of carriers are cyclodextrins, poly vinyl pyrrolidone, phospholipids and poly ethylene glycol etc., |
| Keywords: | Solubility, Dissolution, Bioavailability, kneading method |
| Cite Article: | "A Review on Solubility Enhancement of Water Insoluble Drugs by Various Techniques ", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 6, page no.1142 - 1146, June-2022, Available :http://www.ijrti.org/papers/IJRTI2206180.pdf |
| Downloads: | 000205239 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2206180
Registration ID:182488
Published In: Volume 7 Issue 6, June-2022
DOI (Digital Object Identifier):
Page No: 1142 - 1146 Country: Hyderabad, Telangana, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2206180 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2206180 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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