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Purpose: The spectroscopic method for the Paroxetine HCl bulk drug and pharmaceutical dosage form was developed using methanol as a solvent. The method's linearity was determined by evaluating analyte concentrations ranging from 10mcg/ml to 60mcg/ml. The interday and intraday precision was tested six times (for two days), and the results obtained within and between trial days were expressed as % RSD.
Results: The method holds good linearity from 10-60mcg/ml. The %RSD values of precision studies were found to be below the accepted limit of 2%. The method was found to be linear with a correlation coefficient (R2) of 0.999. The method was also found to be accurate and robust with suitable values.
Conclusion: The results of the study indicated that this method can be used to determine Paroxetine Hydrochloride in bulk medicine and pharmaceutical dosage forms on a regular basis.
"UV - Vis Spectroscopy method to Determination and Validation of Paroxetine Hydrochloride in Bulk and Pharmaceutical Dosage Form", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 6, page no.1358 - 1363, June-2022, Available :http://www.ijrti.org/papers/IJRTI2206204.pdf
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ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator