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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14

Issue per Year : 12

Volume Published : 7

Issue Published : 79

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Paper Title: To The Development Of Externally Applied Age Defying Cosmetic Formulations And Bearing Essential Oils Evaluation
Authors Name: Deepak Kumar Kushawah , Rajat Saxena , Sharmishtha Singh , Kausendra Singh , Subodh Singh
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IJRTI_183901
Published Paper Id: IJRTI2208273
Published In: Volume 7 Issue 8, August-2022
DOI:
Abstract: The present study deals with the evaluation of age defying potential of cosmetic emulsions composed of Red raspberry seed oil, Avocado oil, Pumpkin seed oil, Hemp seed oil, Calendula essential oil, Carrot seed essential oil (oil phase) and Aloe vera gel (aqueous phase). Briefly, cosmetic emulsions were prepared using the hydrophile–lipophile balance (HLB) technique.Various oils, nonionic surfactants (Tween 80 and Span 80), and Aloe vera gel were used as oil phase, emulgents, andemulsion stabilizer, respectively. The formed emulsions firmly withstand 15 min of centrifugation at 3000 rpm. The prepared cosmetic emulsions were also evaluated for Sun Protection Factor (SPF), skin irritation studies, in vitro antioxidant activity, in vitro enzyme inhibition assay and histopathological studies. 1,1-Diphenyl-2-picrylhydrazyl- (DPPH) and nitric oxide-free radical scavenging assay showed good antioxidant potential of the prepared emulsions (A1 & A2).The highest SPF value (21.8) was shown formulation A1. On the basis of SPF values formulation A1 was selected for in-vitro Anti-collagenase & Anti-elastase assays. cosmetic emulsion formulations exhibited negligible skin irritation when tested on Wistar Albino rats. From the enzyme analysis it was observed that formulation A1 exhibited potent Elastase inhibition activity (111.2% at 1μg/ml concentration) and very mild Collagenas inhibition activity (16.5% at 500μg/ml concentration). Histopathological data suggest that the formulation A1s has sufficient potential to be used as potential skin rejuvenating cosmetic preparation.
Keywords: Age defying, fennel seed oil, skin irritation, Antioxidant Activities,DPPH, Nitric oxide.
Cite Article: "To The Development Of Externally Applied Age Defying Cosmetic Formulations And Bearing Essential Oils Evaluation", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 8, page no.1767 - 1783, August-2022, Available :http://www.ijrti.org/papers/IJRTI2208273.pdf
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ISSN: 2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publication Details: Published Paper ID: IJRTI2208273
Registration ID:183901
Published In: Volume 7 Issue 8, August-2022
DOI (Digital Object Identifier):
Page No: 1767 - 1783
Country: Moradabad , Uttar Pradesh , India
Research Area: Pharmacy
Publisher : IJ Publication
Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2208273
Published Paper PDF: https://www.ijrti.org/papers/IJRTI2208273
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED
Journal Starting Year (ESTD) : 2016

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