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Natural products from plants are high in demand due to their low toxicity and easy availability. Molecular docking helps in identifying the best target suitable for the selected drug. This study aimed to evaluate molecular interactions of selected estrogen targets with bioactive compounds of Anastatica hiruchuntica i.e. sylibin. The biological effects of estrogen are mediated by two distinct estrogen receptors (ERs), ERα and ERβ. ER subtype-selective agonists have potential roles in bone and metabolic homeostasis, depression, vasomotor symptoms, neurodegenerative diseases, and cancer. Clinical studies are necessary to validate these compounds as agents for the prevention and treatment of diseases.
Keywords:
Estrogen receptor, Anastatica hiruchuntica
Cite Article:
"ESTROGEN RECEPTOR COMPARED WITH SYLIBIN AS A TARGET FOR POSTMENOPAUSAL SYMPTOMS VIA MOLECULAR DOCKING", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 12, page no.449 - 450, December-2022, Available :http://www.ijrti.org/papers/IJRTI2212060.pdf
Downloads:
000205262
ISSN:
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator