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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21514
Article Published : 8514
Total Authors : 22401
Total Reviewer : 805
Total Countries : 158
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| Paper Title: | Review On Pharmaceutical Preformulation Physicochemical Studies In Formulation And Development Of New Drug Molecules |
| Authors Name: | Vedanti S.Nalkande , Nikhil S.Wagh , Dr.A.M Wankhede |
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| Author Reg. ID: |
IJRTI_184991
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| Published Paper Id: | IJRTI2212093 |
| Published In: | Volume 7 Issue 12, December-2022 |
| DOI: | |
| Abstract: | Abstract—Preformulation Commences When Newly Synthesized Drug show's Sufficient Pharmacologic Promise In Animal Models To Warrant Evaluation In Man. These Studies Should Focus On Those Physicochemical Properties Of The New Compound That Could Affect Drug Performance And Development Of An Efficacious Dosage form. A thorough understanding of these properties may ultimately provide a rational for formulation design or support the need for molecular modification. This review article focus on the various preformulation factors which effect the development of new dosage form like drug solubility, partition coefficient, dissolution rate, polymorphic forms and stability. Every drug has intrinsic chemical and physical properties which has been consider before development of pharmaceutical formulation. This property provides the framework for drug’s combination with pharmaceutical ingredients. Preformulation studies carried out by various research scientists are reviewed. Preformulation studies conduct for newly synthesized compounds or extracted compound and it gives the information regarding the degradation process, any adverse conditions relevant to the drug, bioavailability, pharmacokinetics and formulation of similar compound and toxicity. |
| Keywords: | 6640 |
| Cite Article: | "Review On Pharmaceutical Preformulation Physicochemical Studies In Formulation And Development Of New Drug Molecules ", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.7, Issue 12, page no.607 - 612, December-2022, Available :http://www.ijrti.org/papers/IJRTI2212093.pdf |
| Downloads: | 000205374 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2212093
Registration ID:184991
Published In: Volume 7 Issue 12, December-2022
DOI (Digital Object Identifier):
Page No: 607 - 612 Country: Daryapur, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2212093 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2212093 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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