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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: March 2026
Volume 11 | Issue 3
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21604
Article Published : 8531
Total Authors : 22438
Total Reviewer : 805
Total Countries : 159
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| Paper Title: | Synthesis of Selenium Nanoparticles from neem seeds, and their antibacterial and anticancer activities against Vibrio cholerae and Breast cancer cell lines. |
| Authors Name: | P.JEGANATHAN , Dr. M. Muthukani |
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IJRTI_201342
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| Published Paper Id: | IJRTI2503088 |
| Published In: | Volume 10 Issue 3, March-2025 |
| DOI: | |
| Abstract: | In recent years, the synthesis of nanoparticles using plant-derived extracts has garnered significant attention due to its eco-friendly nature and potential biomedical applications. This study investigates the synthesis of selenium nanoparticles (SeNPs) from Azadirachta indica (neem) seeds and evaluates their antibacterial and anticancer activities. Selenium nanoparticles were synthesized by reducing sodium selenite with the aqueous extract of neem seeds. The synthesis process was characterized by UV-Vis spectroscopy, scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analysis, confirming the formation of spherical nanoparticles with an average size of 30-50 nm. The antibacterial potential of the SeNPs was assessed against Vibrio cholerae, a major causative agent of cholera, using disc diffusion and minimum inhibitory concentration (MIC) methods. The SeNPs exhibited significant antibacterial activity, with a clear inhibition zone and a low MIC, indicating their potential as a therapeutic agent for cholera. Furthermore, the cytotoxic effects of the SeNPs were evaluated on breast cancer cell lines (MCF-7) using MTT assays. The SeNPs showed a dose-dependent reduction in cell viability, suggesting potent anticancer activity. This study highlights the potential of neem seed-derived selenium nanoparticles as a promising candidate for antimicrobial and anticancer therapies, offering an environmentally sustainable alternative for treating bacterial infections and cancer. |
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| Cite Article: | "Synthesis of Selenium Nanoparticles from neem seeds, and their antibacterial and anticancer activities against Vibrio cholerae and Breast cancer cell lines.", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 3, page no.a715-a730, March-2025, Available :http://www.ijrti.org/papers/IJRTI2503088.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2503088
Registration ID:201342
Published In: Volume 10 Issue 3, March-2025
DOI (Digital Object Identifier):
Page No: a715-a730 Country: Bangalore, Karnataka, India Research Area: Biological Science Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2503088 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2503088 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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