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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Issue: March 2026
Volume 11 | Issue 3
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Impact Factor : 8.14
Issue per Year : 12
Volume Published : 11
Issue Published : 118
Article Submitted : 21604
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| Paper Title: | Optimized Terminalia arjuna Phytosomes: A Promising Approach for Cardiovascular Health |
| Authors Name: | Rajshree Nagane , Dr.Swati Patil , Neeraj Chormale |
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| Author Reg. ID: |
IJRTI_188925
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| Published Paper Id: | IJRTI2503098 |
| Published In: | Volume 10 Issue 3, March-2025 |
| DOI: | |
| Abstract: | Cardiovascular diseases continue to pose a significant threat to global health, necessitating innovative therapeutic strategies. In this study, we focused on harnessing the potential of Terminalia arjuna, a revered medicinal plant in Ayurvedic medicine, for cardiovascular applications. We formulated and characterized Terminalia arjuna phytosomes, utilizing a unique approach to enhance their bioavailability and efficacy. The study involved a comprehensive extraction process, and the development of phytosomes using a solvent injection method. Quality by Design (QbD) principles guided the optimization process, ensuring the formulation's stability and effectiveness. Various analytical techniques, including UV-Vis spectroscopy, DSC, and FTIR, were employed to characterize the phytosomal formulation. Our results demonstrated that the optimized phytosomes exhibited superior stability, a favorable particle size, and high entrapment efficiency. Furthermore, the formulation displayed sustained release properties, potent antioxidant activity, and significant pro-angiogenic effects, highlighting its potential therapeutic benefits for cardiovascular health. The pro-angiogenic activity observed in the chick chorioallantoic membrane (CAM) assay suggests the formulation's ability to promote blood vessel formation, crucial for tissue repair and healing. In conclusion, our study presents a novel approach to harnessing the medicinal properties of Terminalia arjuna through phytosomal formulation. The optimized phytosomes show promising potential as a therapeutic agent for cardiovascular diseases, addressing both antioxidant and pro-angiogenic aspects. This research opens new avenues for herbal medicine, emphasizing the importance of enhancing bioavailability and stability for maximizing the therapeutic impact of natural compounds. |
| Keywords: | : Terminalia arjuna, Phytosome, Analytical evaluations, Kinetic studies, Pro-angiogenic activity |
| Cite Article: | "Optimized Terminalia arjuna Phytosomes: A Promising Approach for Cardiovascular Health", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 3, page no.a791-a804, March-2025, Available :http://www.ijrti.org/papers/IJRTI2503098.pdf |
| Downloads: | 000546 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2503098
Registration ID:188925
Published In: Volume 10 Issue 3, March-2025
DOI (Digital Object Identifier):
Page No: a791-a804 Country: Thane , Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2503098 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2503098 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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