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International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | FORMULATION AND EVALUATION OF ENTERIC COATED TABLET OF PROTON PUMP INHIBITOR ESOMEPRAZOLE: A REVIEW |
| Authors Name: | AMAR ANAND , REDDY NAZEMOON |
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IJRTI_201472
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| Published Paper Id: | IJRTI2504003 |
| Published In: | Volume 10 Issue 4, April-2025 |
| DOI: | |
| Abstract: | In this research, the Enteric Coated Tablet of Proton Pump Inhibitor Esomeprazole which evaluate the formulation for various parameter to release the active ingredient after predetermine time in a predetermine location with better pharmaceutical and therapeutic properties. Different core tablets were prepared and formulation (F-1) was selected for further enteric coating, based on the disintegration time. Matrix coating was applied to achieve 6% weight gain using Enteric coating was carried out using different polymers like Eudragit FS 30 D, Eudragit S-100, Triethyl citrate to protecting all the drug formulation from acidic environment. Which results entric coating protect acid-liable drugs from the gastric fluid and inhance the bioavailability and reduce the toxicity by slowing drug absorption. From disintegration time and dissolution rate studies indicate that all the esomeprazole enteric tablets prepared possess good integrity, desirable for enteric coated tablets. Among the polymers studied, Stability studies indicate that the prepared formulations were stable for a period of three months. This study concluded that enteric coated tablets of esomeprazole can be prepared using any of the enteric coating polymer studied using a minimal weight gain of 6%. |
| Keywords: | Enteric coating tablets, Esomeprazole, Eudragit, HPMCP, CAP, stability. |
| Cite Article: | "FORMULATION AND EVALUATION OF ENTERIC COATED TABLET OF PROTON PUMP INHIBITOR ESOMEPRAZOLE: A REVIEW", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 4, page no.a17-a27, April-2025, Available :http://www.ijrti.org/papers/IJRTI2504003.pdf |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2504003
Registration ID:201472
Published In: Volume 10 Issue 4, April-2025
DOI (Digital Object Identifier):
Page No: a17-a27 Country: HYDERABAD , TELANGANA , INDIA Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2504003 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2504003 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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