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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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| Paper Title: | COMPARATIVE STUDY OF ANTI-TUBERCULAR DRUGS : A COMPREHENSIVE REVIEW |
| Authors Name: | Ms.Sanjana H.Ramani , Dr.Jameel Abbas |
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IJRTI_204421
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| Published Paper Id: | IJRTI2506088 |
| Published In: | Volume 10 Issue 6, June-2025 |
| DOI: | |
| Abstract: | Drug resistance, co-infections, and social determinants of health are some of the elements that make tuberculosis (TB) a persistent danger to world health. Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), which mainly affects the lungs but can potentially affect other organs. Poverty, malnourishment, crowded living situations, and immunocompromised conditions like HIV/AIDS are risk factors for tuberculosis. Cough, fever, weight loss, and night sweats are some of the symptoms of tuberculosis (TB), though these might change based on the infection site. Rapid molecular assays, imaging studies, microbiological testing, and clinical evaluation are usually used in the diagnosis process. Multidrug therapy is used for six to nine months of treatment; lengthier and more complicated regimens are needed for drug-resistant TB. The etiology, symptoms, diagnosis, pathophysiology, epidemiology, and therapy of both pulmonary tuberculosis (PTB) and extra-pulmonary tuberculosis (EPTB) have all been covered in this review article. The first-line medications are isoniazid, rifampicin, pyrazinamide, ethambutol, and streptomycin. Our goal was to assess the factors that influence pharmacokinetic variance and to characterize the pharmacokinetics of rifampin, isoniazid, pyrazinamide, and ethambutol in TB patients who were started on first-line therapy regimens. Each drug's 2-hour level, plasma concentration-time, and area under the curve for 0–8-hour profiles were determined. |
| Keywords: | Tuberculosis, Isoniazid, Rifampicin, Pyrazinamide, Ethambutol, Streptomycin |
| Cite Article: | "COMPARATIVE STUDY OF ANTI-TUBERCULAR DRUGS : A COMPREHENSIVE REVIEW", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 6, page no.a742-a758, June-2025, Available :http://www.ijrti.org/papers/IJRTI2506088.pdf |
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| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2506088
Registration ID:204421
Published In: Volume 10 Issue 6, June-2025
DOI (Digital Object Identifier):
Page No: a742-a758 Country: Jalgaon, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2506088 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2506088 |
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ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
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