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International Journal for Research Trends and Innovation
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ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
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Impact Factor : 8.14
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| Paper Title: | A REVIEW ON PHARMACEUTICAL IMPORTANT NATURAL EXCIPIENTS |
| Authors Name: | Vaishnavi R. Shahare , Prasad R. Deshmukh , Tejas S. Dhok , Dipti B. Ruikar |
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IJRTI_205035
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| Published Paper Id: | IJRTI2506207 |
| Published In: | Volume 10 Issue 6, June-2025 |
| DOI: | |
| Abstract: | The increasing demand for sustainable and biocompatible excipients in pharmaceutical formulations is driven by regulatory support and consumer preference for natural products. This review examines the pharmaceutical potential of selected natural excipients—neem gum (Azadirachta indica), guar gum (Cyamopsis tetragonoloba), gum ghatti (Anogeissus latifolia), khaya gum (Khaya senegalensis), tamarind seed gum (Tamarindus indica), and agar (from Gelidium and Gracilaria spp.). A comprehensive analysis of peer-reviewed literature was conducted to evaluate their physicochemical properties, extraction and purification techniques, and roles in various dosage forms. Each excipient demonstrated multifunctional utility: neem gum exhibited gel-forming and controlled-release capabilities; guar gum showed mucoadhesive and sustained-release potential; gum ghatti functioned effectively as a thickening and emulsifying agent in colon-targeted formulations; khaya gum served as a binder and stabilizer in suspensions; tamarind seed gum provided excellent bio-adhesion and rapid disintegration in orally disintegrating tablets; and agar proved effective as a gelling agent in controlled-release systems. Natural excipients offer advantages such as biodegradability, low toxicity, and cost-effectiveness. However, challenges like batch-to-batch variability, microbial contamination, and formulation stability must be addressed through further standardization and regulatory harmonization. This review highlights their promising role in developing eco-friendly, patient-compliant, and regulatory-aligned pharmaceutical formulations |
| Keywords: | Natural Excipients, Pharmaceutical Excipients, Gum, Guar, Ghatti, Khaya Gum, Tamarind Seed Gum, Agar, Drug Delivery Systems, Biocompatibility, Plant-based Polymers, Binders, Disintegrants, Stabilizers, Gelling Agents, Mucoadhesive Agents, Controlled Release, Sustainable Formulations, Herbal Excipients, Excipient Purification. |
| Cite Article: | "A REVIEW ON PHARMACEUTICAL IMPORTANT NATURAL EXCIPIENTS", International Journal for Research Trends and Innovation (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 6, page no.c47-c54, June-2025, Available :http://www.ijrti.org/papers/IJRTI2506207.pdf |
| Downloads: | 000382 |
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2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
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Published Paper ID: IJRTI2506207
Registration ID:205035
Published In: Volume 10 Issue 6, June-2025
DOI (Digital Object Identifier):
Page No: c47-c54 Country: Amravati, Maharashtra, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2506207 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2506207 |
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ISSN: 2456-3315
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