 |
International Journal for Research Trends and Innovation
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2456-3315 | Impact factor: 8.14 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.14 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
|
Issue: December 2025
Volume 10 | Issue 12
Review Result and Publication of Paper within : 2-3 days
Click Here For more DetailsFor Authors
Forms / Download
Published Issue Details
Editorial Board
Other IMP Links
Facts & Figure
Impact Factor : 8.14
Issue per Year : 12
Volume Published : 10
Issue Published : 115
Article Submitted : 19445
Article Published : 8041
Total Authors : 21252
Total Reviewer : 769
Total Countries : 144
Indexing Partner
Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
Published Paper Details
|
|
| Paper Title: | A REVIEW- POLYMER-BASED NANOPARTICLES AS ORAL ANTICANCER DRUG DELIVERY SYSTEMS |
| Authors Name: | Umesh Kumar chaurasiya , Dr. Deepika Gupta , Dr. Sudha vengurlekar , Dr. Sachin kumar jain |
| Download E-Certificate: | Download |
| Author Reg. ID: |
IJRTI_206167
|
| Published Paper Id: | IJRTI2510062 |
| Published In: | Volume 10 Issue 10, October-2025 |
| DOI: | |
| Abstract: | Breast cancer (BC) becomes the most commonly diagnosed cancer among women around the globe. Oral chemotherapy is preferred in the first place for its convenience and potential to improve patient’s quality of life. Non-invasiveness along with improved patient convenience is the biggest ostensible advantage of orally administered drugs. Oral therapy reduces the cost of inpatient and ambulatory patient care services, and ancillary support by healthcare personnel like nurses and technicians. However, oral delivery is restricted by various physicochemical constraints. The significant physicochemical constraints to the efficient oral absorption of anticancer drugs include poor solubility in the aqueous intestinal milieu. In addition, they are either substrates for the biological transporters including P-glycoprotein (P-gp), metabolizing enzyme, cytochrome P450, or both, resulting in a considerable loss owing to their expulsion or first-pass metabolism. Polymer-lipid hybrid nanoparticles (PLHNPs) are an emerging nanocarrier platform made from building blocks of polymers and lipids. PLHNPs integrate the advantages of biomimetic lipid- based nanoparticles (i.e., solid lipid nanoparticles and liposomes) and biocompatible polymeric nanoparticles. The hybrid architecture can provide advantages such as controllable particle size, surface functionality, high drug loading, tunable drug release profile, and improved stability in GIT. |
| Keywords: | nanoparticles, hybrid, polymers, drug release profile |
| Cite Article: | "A REVIEW- POLYMER-BASED NANOPARTICLES AS ORAL ANTICANCER DRUG DELIVERY SYSTEMS", International Journal of Science & Engineering Development Research (www.ijrti.org), ISSN:2455-2631, Vol.10, Issue 10, page no.a616-a630, October-2025, Available :http://www.ijrti.org/papers/IJRTI2510062.pdf |
| Downloads: | 000110 |
| ISSN: |
2456-3315 | IMPACT FACTOR: 8.14 Calculated By Google Scholar| ESTD YEAR: 2016 An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.14 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator |
| Publication Details: |
Published Paper ID: IJRTI2510062
Registration ID:206167
Published In: Volume 10 Issue 10, October-2025
DOI (Digital Object Identifier):
Page No: a616-a630 Country: Chhatarpur, Madhya Pradesh, India Research Area: Pharmacy Publisher : IJ Publication Published Paper URL : https://www.ijrti.org/viewpaperforall?paper=IJRTI2510062 Published Paper PDF: https://www.ijrti.org/papers/IJRTI2510062 |
| Share Article: | |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijrti.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
ISSN Details
 |
 |
|
ISSN: 2456-3315
Impact Factor: 8.14 and ISSN APPROVED,
Journal Starting Year (ESTD) : 2016
DOI (A digital object identifier)
| Providing A digital object identifier by DOI.ONE How to Get DOI? |
Conference
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Important Details
Join RMS/Earn 300
WhatsApp
Click Here
Click Here
Indexing Partner |
|||
| Copyright © 2025 - All Rights Reserved - IJRTI | |||